HIV-associated dementia: Prompt response to zidovudine
نویسندگان
چکیده
منابع مشابه
HIV-associated Dementia
Epidemiology of HIV Dementia The World Health Organization (WHO) estimates that worldwide there are 40 million people living with HIV/AIDS in 2003, and there were 3 million AIDS deaths in 2003. This total does not include the 20 million people around the world who have already died of AIDS. There were 5 million people newly infected with HIV in 2003. The vast majority, 26.6 million people, almo...
متن کاملHIV-Associated Dementia and Aging
HIV/AIDS research over the past 2 decades has focused with near exclusion on younger individuals (less than 50 years of age). Research involving older HIV-seropositive individuals is notably lacking. By and large, this reflects the preponderance of disease in younger individuals, but may also reflect a selection bias due to study designs. Coexisting medical conditions, which are more common in ...
متن کاملWhat's in a name? AIDS dementia complex, HIV-associated dementia, HIV-associated neurocognitive disorder or HIV encephalopathy.
The current paper reviews currently used and proposed nomenclature for neurocognitive disorders associated with HIV, and proposes a unitary system as well as recommends an operational approach to screening/diagnosing severe forms of HIV associated neurocognitive disorder (HAND) in order to identify individuals who might benefit from antiretrovirals (ARVs). The terms HIV dementia complex, HIV-as...
متن کاملRisk of HIV dementia and opportunistic brain disease in AIDS and zidovudine therapy.
OBJECTIVE To determine the incidence of HIV dementia and opportunistic brain disease in AIDS relative to the use of licensed antiretoviral medication (zidovudine, zalcitabine, didanosine, and stavudine). METHOD Medical records were evaluated retrospectively in a longitudinal cohort of 1109 patients with AIDS during the period 1991-4. Treatment groups were defined by start and duration of zido...
متن کاملMacrophages and HIV-1-associated dementia.
One of the strongest predictors for HIV-1-associated dementia is the presence of monocytic infiltration in perivascular areas of the brain. Therefore, macrophages have been suggested to play a major role in the development of this disease. This review focuses on possible mechanisms through which the macrophage may enhance disease progression by mediating neuronal damage.
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ژورنال
عنوان ژورنال: Neurology: Clinical Practice
سال: 2014
ISSN: 2163-0402,2163-0933
DOI: 10.1212/cpj.0000000000000035